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KMID : 0882420160910010075
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Korean Journal of Medicine
2016 Volume.91 No. 1 p.75 ~ p.78
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Acute Myeloid Leukemia with the 11q23 Rearrangement in a Patient with Klinefelter Syndrome
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Jeong Young-Hoon
Shim Hyeok
Lee Young-Jin
Park Moo-Rim
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Abstract
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Klinefelter syndrome is usually characterized by eunuchoidism, gynecomastia, small testes, infertility, elevated gonadotropins, mental retardation, and a constitutional extra X chromosome. Several reports have suggested an association between leukemia and Klinefelter syndrome, although two cohort studies failed to show a clear association between the two. We report the first Korean case of acute myeloid leukemia with the 11q23 rearrangement in a 27-year-old man with Klinefelter syndrome.
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KEYWORD
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Klinefelter syndrome, Leukemia, Myeloid, Acute
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